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What is a Comma Free Code?
comma-free code: A code constructed so that any partial code word, beginning at the start of a code word but terminating prior to the end of that code word, is not a valid code word. Note 1: The comma-free property permits the proper framing of transmitted code words when (a) external synchronization is provided to identify the start of the first code word in a sequence of code words and (b) no uncorrected errors occur in the symbol stream.
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http://www.its.bldrdoc.gov/fs-1037/dir-008/_1079.htm
Sources
http://www.sigmaxi.org/amsci/issues/Comsci98/compsci9801.html